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4.41 from 60 votes

Creamy Baked Tilapia & Spinach Casserole

This Creamy Baked Tilapia Casserole is layered over spinach and smothered in a creamy sauce that can be ready within 10 minutes once it hits the oven.
Prep Time7 mins
Cook Time10 mins
Total Time17 mins
Course: Fish Casserole
Cuisine: American
Keyword: Baked Fish, Baked Tilapia Recipes, Tilapia Recipes
Servings: 8
Calories: 279kcal
Author: Alyona's Cooking


  • 5 tilapia fillets 1lb
  • 8 oz bag of fresh spinach
  • 3 tbsp butter sliced
  • 1 cup shredded Monterey jack cheese


  • 1/2 cup mayonnaise
  • 1/2 cups grated parmesan cheese
  • 2 cloves garlic crushed
  • 1/2 cup sour cream
  • 1 tsp old bay seasoning
  • 1/2 tsp adobo seasoning
  • 1/4 tsp black pepper
  • 1/4 tsp salt


  • Pack spinach onto the bottom of a baking dish. Top with butter slices and layer the fish fillets over the top.
  • Then, combine the sauce ingredients and evenly spread over the top of the casserole.
  • Finally, sprinkle with cheese and bake in a preheated to 500 degrees F oven for 10 minutes.
  • Enjoy


Serving: 1g | Calories: 279kcal | Carbohydrates: 6.1g | Protein: 20.1g | Fat: 20.2g | Saturated Fat: 10.3g | Cholesterol: 72mg | Sodium: 556mg | Fiber: 0.7g | Sugar: 1.2g